Newborn Screening

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November 21, 2009

Collection of Screening Specimens


	The specimens are samples of blood collected from infants by saturating marked areas of a filter paper card with blood obtained by skin puncture of the heel. In recognition of the role of Dr. Robert Guthrie in newborn screening, the specimen is now called the Guthrie spot. Each state has its own collection form on which some basic demographic information as well as the blood collection spots are recorded. Many factors determine the acceptability and quality of a specimen: the timing of collection, the provision of patient and specimen information, the collection of the blood specimen, and its subsequent handling. Problems with any of these may render a specimen invalid.

	Collection of Screening Specimens


		Timing of Specimen Collection

		Collection of Blood Specimen

		Specimen Handling

		Invalid Specimens


		March of Dimes Newborn Screening Recommendations

		Clinical Issues and Considerations
		-	Introduction and History
		-	Collection of Screening Specimens
		-	Disorders: Description and Sample Screening Methodology
		-	Results and Follow-up
		-	Parent Education
		-	Professional Education
		-	Frequently Asked Questions
		-	Glossary of Newborn Screening Acronyms and Abbreviations

		What Providers Can Do

		Resources for Families
		-	March of Dimes Information for Families
		-	Ask the March of Dimes Now
		-	Other Resources



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