May 23, 2013

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    Newborn Screening

Severe Combined Immunodeficiency: US, January 6, 2013
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• Currently 7 states, representing approximately 28% of live births in the United States, screen for Severe Combined Immunodeficiency. 
• In the United States, screening for the 31 core newborn screening conditions is not universally required by rule or law and fully implemented in any state. 
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  Footnotes
•  For more information on the core disorders, see the August 2004 report Newborn Screening: Toward a Uniform Screening Panel and Systems, developed by the American College of Medical Genetics and Evidence Review report on SCID, prepared by the Advisory Committee on heritable Disorders in Newborns and Children.
•  For more detailed information on newborn screening status, please see the National Newborn Screening Status Report developed by the National Newborn Screening and Genetics Resource Center.
•  SCID=Severe Combined Immunodeficiency
•  Severe combined immunodeficiency (SCID) is a term that describes a group of rare inherited disorders characterized by defects in two critical immune system cells that are normally mobilized by the body to combat infections. SCID has also been referred to in the popular media as the "bubble boy disease." Without treatment, infants with SCID are more susceptible to and can develop recurrent infections, leading to failure to thrive and oftentimes death.
  Source
•  National Newborn Screening and Genetics Resource Center.
•  Retrieved May 23, 2013, from www.marchofdimes.com/peristats.

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